Slacker actress Jane F, is having a bad day that is getting more outrageous by the minute. Jane’s misadventures begin when she treats herself to a batch of cupcakes left unattended by her psycho roommate (Danny Masterson) that prove not as innocent as they appear. She then bums a ride from her roommate’s friend (John Krasinski)and attempts to cross town so she can repay an unforgiving drug dealer, attend an audition, and somehow replace the precious cupcakes. Enjoy the wild journey as Jane’s efforts to get through her day prove an arduous task of epic proportions.

Struggling artist David (Luke Wilson) has big plans for his life... except he can't exactly remember what they are. When slinky, sassy Serena (Alicia Witt) waltzes into his life things take a definite turn for the better, that is, until his house burns down and she bolts to New York with a wannabe rock star (Jamie Kennedy). While Serena frolics back east, lovesick David gets by with a little help from his friends... like singing farmer (Jack Black), hilariously sarcastic sidekick (Andy Dick) and oversexed rich girl (Brittany Murphy). If Serena ever returns, someone's gonna get a rude awakening, as this raucous comedy hurtles toward an outrageous and unexpected finish!